Ingriedients: 
Hexahydrocannabinol, colorants, flavorings, glucose syrup

Cannabinoids

At Space Express, you can purchase cannabinoids solely for research-related purposes. Cannabinoids artificially produced in the laboratory exert their influence on the brain and other organs in a manner similar to delta-9-tetrahydrocannabinol (THC), the most active component in cannabis, whether it be hashish or marijuana. These lab-synthesized cannabinoids have the capacity to mimic the effect of cannabis in an artificial manner, and this imitation often exhibits a more intense impact compared to naturally occurring cannabinoids in the plant.

What are Cannabinoids?
Cannabinoids are a class of chemical compounds that naturally occur in the cannabis plant (Cannabis sativa). They are known for their interaction with the endocannabinoid system, a complex network of receptors and signaling molecules involved in regulating various physiological processes in the human body. The two most well-known cannabinoids are: Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD).
THC is the primary psychoactive compound in cannabis and is responsible for the “high” or intoxicating effect associated with marijuana use.
In contrast to THC, CBD does not have psychoactive effects. It is known for its interaction with the endocannabinoid system and is being investigated for potential therapeutic applications.
In addition to THC and CBD, there are many other cannabinoids in cannabis, including cannabigerol (CBG), cannabichromene (CBC), cannabinol (CBN), and more. Each cannabinoid has different interactions with the receptors of the endocannabinoid system, resulting in diverse effects on the body.
Cannabinoids can be both endogenous (produced by the body itself) and exogenous (derived from plants, particularly cannabis). They are often used for medicinal purposes, with CBD, for example, being researched for potential applications in conditions such as epilepsy, anxiety, and inflammatory diseases.
Synthetic cannabinoids are sometimes referred to as “research chemicals” because they are initially manufactured for research purposes and are often not fully studied regarding their safety and effects on the human body. They can vary in chemical composition and potency and are sometimes used in laboratories to understand their specific interactions with cannabinoid receptors.

Effects of Cannabinoids:
The effects of cannabinoids can vary depending on the specific cannabinoid, dosage, method of consumption, individual sensitivity, and other factors. Here are some common effects associated with the use of cannabinoids, especially delta-9-tetrahydrocannabinol (THC), the primary psychoactive component in cannabis:
Euphoria: Many users experience a sense of intense happiness and well-being.
Relaxation: Cannabinoids, especially THC, are known for their calming and relaxing effects.
Altered perception: Users may experience a change in sensory perception, such as increased sensitivity to colors and sounds.
Increased appetite: Often, an increased need for food, also known as “munchies,” is associated with the use of cannabinoids.
Changes in cognitive functions: The use of cannabinoids can affect thinking, concentration, and memory.
Reduced pain perception: Cannabinoids are sometimes used for pain relief, as they can reduce the perception of pain.
Anxiety reduction: Some people experience a decrease in feelings of anxiety and stress after using cannabinoids, especially CBD.

It is important to note that the effects may vary between individuals, and not all users will experience the same response. Additionally, different cannabinoids, besides THC, may have different effects. For example, cannabidiol (CBD) is not known for its psychoactive effects but rather for its potential anxiolytic and anti-inflammatory properties.

Duration of Action of Cannabinoids:
The duration of action of cannabinoids, both natural and synthetic, can vary depending on various factors, including the specific cannabinoid, dosage, method of consumption, individual sensitivity, and more. Here are some general observations:

Natural Cannabinoids (e.g., THC, CBD):
Inhalation (smoking, vaping): Effects can occur quickly, usually within minutes, and typically last 1 to 3 hours.
Oral consumption (edibles): It may take longer for effects to occur, usually within 30 minutes to 2 hours after consumption, and the duration may be longer, often 4 to 6 hours or even longer.

Synthetic Cannabinoids (e.g., Research chemicals):
Inhalation (smoking, vaping): Effects can occur quickly, similar to natural cannabinoids, but the duration may sometimes be longer.
Oral consumption: Similar to natural cannabinoids, it may take longer for effects to occur, and the duration may vary, but synthetic cannabinoids can sometimes be more potent and longer-lasting than natural ones.

The exact duration of action can vary greatly between different synthetic cannabinoids, as their chemical composition often varies. Additionally, individual responses may vary, and the effects of cannabinoids can be influenced by factors such as a person’s overall health, frequency of use, tolerance, and more.

Dosage of Cannabinoids:
Dosing cannabinoids, both natural and synthetic, requires caution and responsibility. Here are some considerations:

Know what you’re using: Make sure you are familiar with the specific cannabinoid or product you are using, including potential effects and risks.
Know your tolerance: If you use cannabinoids regularly, your tolerance may increase. Keep this in mind when dosing.
Wait between doses: Especially with edibles, the effect may take some time. Do not take additional doses too quickly to prevent excessive use.

Natural Cannabinoids (e.g., THC, HHC, CBD):
Inhalation (smoking, vaping): Start with a small amount and wait a few minutes to assess the effects before using more. The effect occurs quickly but can be intense.
Oral consumption (edibles): Start with a low dose, as it may take longer for effects to occur. Wait at least 2 hours before considering taking more.

Synthetic Cannabinoids (e.g., Research chemicals):
Be cautious: It is advisable to approach dosing synthetic cannabinoids with caution due to their potency and the unpredictability of effects.
Start low: Begin with a very low dose to assess individual response. Be aware of potential risks and side effects.

Chemical Composition of Cannabinoids:

Cannabinoids are a class of chemical compounds specifically found in the cannabis plant (Cannabis sativa). The main cannabinoids are derived from cannabigerolic acid (CBGA), which is converted into cannabidiolic acid (CBDA) and tetrahydrocannabinolic acid (THCA) through biosynthetic routes. These acids undergo decarboxylation (loss of carbon dioxide) upon heating or drying, resulting in the active forms of the cannabinoids.
Here are some of the main naturally occurring cannabinoids and their chemical composition:
Delta-9-tetrahydrocannabinol (THC): The main psychoactive substance in cannabis.
Chemical formula: C21H30O2
Cannabidiol (CBD): A non-psychoactive cannabinoid with various potential therapeutic applications.
Chemical formula: C21H30O2
Cannabigerol (CBG): A non-psychoactive precursor of other cannabinoids.
Chemical formula: C21H32O2
Cannabinol (CBN): A breakdown product of THC that often occurs after prolonged storage of cannabis.
Chemical formula: C21H26O2
Cannabichromene (CBC): A cannabinoid with non-psychoactive properties.
Chemical formula: C21H30O2
These cannabinoids have similar structures, with an aromatic ring and a chain of carbon atoms. The differences in their effects arise from subtle variations in their chemical structure and how they interact with the cannabinoid receptors in the body’s endocannabinoid system. Research on cannabinoids and their potential medicinal applications is still in its early stages.

Mechanism of Action of Cannabinoids:
The mechanism of action of cannabinoids is based on their interaction with the endocannabinoid system (ECS) in the human body. The endocannabinoid system is a complex network of receptors, endogenous (body-produced) ligands (endocannabinoids), and enzymes involved in regulating various physiological processes.

There are two major types of receptors in the endocannabinoid system:

Cannabinoid receptor type 1 (CB1): These receptors are primarily found in the brain and central nervous system.
Cannabinoid receptor type 2 (CB2): These receptors are mainly found in the immune system and peripheral tissues.

The main mechanisms of action of cannabinoids include:

Agonism: Some cannabinoids, such as delta-9-tetrahydrocannabinol (THC), act as agonists of cannabinoid receptors. They bind to these receptors and activate them, leading to physiological responses. CB1 receptors are primarily activated in the brain, explaining the psychoactive effects of THC.
Antagonism: Other cannabinoids can act as antagonists of cannabinoid receptors. They block the activation of receptors by agonists, reducing physiological responses.
Modulation of neurotransmitters: Cannabinoids can regulate the release of neurotransmitters, such as gamma-aminobutyric acid (GABA) and glutamate, affecting neuronal activity and communication.
Influence on enzymes: Cannabinoids can affect the activity of enzymes within the endocannabinoid system, such as inhibiting enzymes involved in the breakdown of endocannabinoids.

The endocannabinoid system is involved in regulating various physiological processes, including mood, appetite, pain perception, immune function, and sleep. The interaction of cannabinoids with this system can lead to diverse effects, ranging from pain relief and relaxation to changes in cognitive functions and euphoria. Understanding the precise mechanism of action of specific cannabinoids is still an active area of research.

Buying Cannabinoids?
At SpaceExpress.nl, we strive to provide you with optimal support with all the supplies and information you need for your research. We offer cannabinoids for sale as CBD lollipops, HHC gummies, HHC lollipops, and JWZ-210. This way, you can always find the perfect product for your research purposes. Check out our page on Benzodiazepines or Arylcyclohexylamines for other research-related products.